Technological Innovation in Epigenetics Services: Sequencing Costs Drop to 1/20th Since 2018
Published Date: Tuesday,30 Sep,2025





Epigenetics services are a series of specialized services tailored to the needs of epigenetic research and related applications. Epigenetics investigates the heritable variation in gene expression without altering the DNA sequence. Analysis services utilize technologies such as next-generation sequencing (NGS) to conduct genome-wide epigenetic analyses, such as DNA methylation profiling and chromatin immunoprecipitation sequencing (ChIP-seq), to analyze DNA methylation and demethylation status and their functional impact on cell development and differentiation.
Figure1. Epigenetics Services

The epigenetics services market is experiencing rapid growth with a broad range of application prospects. It is driven by factors such as the increasing prevalence of cancer and the development of personalized medicine. Technological innovation is accelerating, and the market shows a trend of regional differentiation.
The global cancer prevalence is on the rise. According to the WHO, cancer killed about 10 million people in 2020, and the IARC projects 28.4 million new cases by 2040, a 47% increase. This has driven up the demand for epigenetic drugs and diagnostics, as researchers seek more effective, targeted treatments based on gene expression variations.
Technologies such as single-cell epigenomic sequencing have seen significant cost reductions. The cost has dropped to 1/20th of that in 2018, and the market share of domestic sequencing instruments has increased from 12% in 2020 to 31% in 2023, expected to achieve import substitution by 2028.
According to the new market research report “Global Epigenetics Services Supply, Demand and Key Producers, 2025-2031”, published by Global Info Research, the global Epigenetics Services market size is projected to reach USD 0.28 billion by 2031, at a CAGR of 5.6% during the forecast period.
Figure2. Global Epigenetics Services Market Size (US$ Million), 2020-2031

Figure3. Global Epigenetics Services Top 10 Players Ranking and Market Share (Ranking is based on the revenue of 2024, continually updated)

According to Global Info Research Top Players Research Center, the global key manufacturers of Epigenetics Services include Bio-Rad, lllumina, QIAGEN, Thermo Fisher, Active Motif, etc. In 2024, the global top four players had a share approximately 36% in terms of revenue.
Figure4. Epigenetics Services, Global Market Size, Split by Product Segment

In terms of product type, Histone Modification is the largest segment, hold a share of 76%,
Figure5. Epigenetics Services, Global Market Size, Split by Application Segment

In terms of product application, Pharmaceutical and Biotechnology Companies is the largest application, hold a share of 75%,
Figure6. Epigenetics Services, Global Market Size, Split by Region

The subject content of the Epigenetics Services report research consists of 13 chapters:
Chapter 1, to describe Epigenetics Services product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top players of Epigenetics Services, with revenue, gross margin, and global market share of Epigenetics Services from 2019 to 2024.
Chapter 3, the Epigenetics Services competitive situation, revenue, and global market share of top players are analyzed emphatically by landscape contrast.
Chapter 4 and 5, to segment the market size by Type and by Application, with consumption value and growth rate by Type, by Application, from 2019 to 2030.
Chapter 6, 7, 8, 9, and 10, to break the market size data at the country level, with revenue and market share for key countries in the world, from 2019 to 2024.and Epigenetics Services market forecast, by regions, by Type and by Application, with consumption value, from 2025 to 2031.
Chapter 11, market dynamics, drivers, restraints, trends, Porters Five Forces analysis.
Chapter 12, the key raw materials and key suppliers, and industry chain of Epigenetics Services.
Chapter 13, to describe Epigenetics Services research findings and conclusion.
For more information, please refer to "Global Epigenetics Services Market 2025 by Manufacturers, Regions, Type and Application, Forecast to 2031". This report analyzes the supply and demand situation, development status, and changes in the industry, focusing on the development status of the industry, how to face the development challenges of the industry, industry development suggestions, industry competitiveness, and industry investment analysis and trend forecasts. The report also summarizes the overall development dynamics of the industry, including the impact of the latest US tariffs on the global supply chain, the supply relationship analysis of the industrial chain, and provides reference suggestions and specific solutions for the industry in terms of products.
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